2018
J. Jesús Naveja, Mariel P. Rico-Hidalgo, José L. Medina-Franco.
2017
González-Medina M, Naveja J, Sánchez-Cruz N, Medina-Franco JL. Open chemoinformatic resources to explore the structure, properties and chemical space of molecules. RSC ADVANCES, 7, 54153-54163.
Medina-Franco JL and Martinez-Mayorga K. 2018. Uncovering Activity Cliff Generators Using Distribution of SALI Values TIP REVISTA ESPECIALIZADA EN CIENCIAS QUIMICO-BIOLOGICAS, 21, 14-23.
Noemi D. Paguigan, Mohammed H. Al-Huniti, Huzefa A. Raja, Austin Czarnecki, Joanna E. Burdette, Mariana González-Medina, José L. Medina-Franco, Stephen J. Polyak, Cedric J. Pearce, Mitchell P. Croatt, Nicholas H. Oberlies (2017) Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs fluorinated fungal metabolites BIOORGANIC AND MEDICINAL CHEMISTRY, 25 (2017) 5238–5246.
González-Medina M, Owen JR, El-Elimat T, Pearce C, Oberlies N, Figueroa M, Medina-Franco JL. Scaffold Diversity of Fungal Metabolites. FRONTIERS IN PHARMACOLOGY, 8, 180 (2017).
Fernanda I Saldívar-González, J Jesús Naveja, Oscar Palomino-Hernández, José L Medina-Franco (2017) Getting SMARt in Drug Discovery: Chemoinformatics Approaches for Mining Structure-Multiple Activity Relationships RSC ADVANCES, 7: 632-641.
Oscar Méndez-Lucio, José L Medina-Franco (2017) The Many Roles of Molecular Complexity in Drug Discovery DRUG DISCOVERY TODAY 22: 120-126
Fernanda Saldívar-González, Fernando D Prieto-Martínez, José L Medina-Franco (2017) Drug Discovery and Development: A Computational Approach EDUCACION QUIMICA 28: 51-58.
2016
Mariana González-Medina, Fernando Daniel Prieto-Martínez, John R. Owen, José L Medina-Franco (2016) Consensus Diversity Plots: a global diversity analysis of chemical libraries JOURNAL OF CHEMINFORMATICS, 8(1):63.
Oscar Méndez-Lucio, J Jesús Naveja, Hugo Vite-Caritino, Fernando Daniel Prieto-Martínez, José L Medina-Franco (2016) One Drug for Multiple Targets: A Computational Perspective JOURNAL OF THE MEXICAN CHEMICAL SOCIETY, 60: 168-181.
Elena Pacheco-Martínez, Evangelina Figueroa-Medina, Carlos Villarreal, Germinal Cocho, José L Medina-Franco, Oscar Méndez-Lucio, Leonor Huerta (2016) Statistical correlation of nonconservative substitutions of HIV gp41 variable amino acid residues with the R5X4 HIV-1 phenotype VIROLOGY JOURNAL 13:28.
Fahad S Aldawsari, Rodrigo Aguayo-Ortiz, Kanishk Kapilashrami, Jakyung Yoo, Minkui Luo, José L Medina-Franco, Carlos A Velázquez-Martínez (2016) Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 31(5),695-703.
2015
José L Medina-Franco, Eli Fernández-De-Gortari y J Jesús Naveja (2015) Progress in computer-aided drug design EDUCACION QUIMICA 26: 180-186 JUL15.
De la Cruz-Hernández, E, Medina-Franco, J L Trujillo, J, A Chávez-Blanco, G Domínquez-Gómez, E Pérez-Cárdenas, A González-Fierro, L Taja-Chayeb, A Duenas-Gonzalez (2015) Ribavirin as a tri-targeted antitumor repositioned drug ONCOLOGY REPORTS 33: 2384-2392 MAY 2015.
Rajarshi Guha, José L Medina-Franco (2014) On the Validity versus Utility of Activity Landscapes: Are all Activity Cliffs Statistically Significant? JOURNAL OF CHEMINFORMATICS 6: 11 APR 2014.
José L Medina-Franco, Oscar Méndez-Lucio, Jakyung Yoo (2014) Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-fit Docking INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15: 3253-3261 FEB 2014.
2014
Katie R Martin, Pooja Narang, José L Medina-Franco, Nathalie Meurice, Jeffrey P MacKeigan (2014) Integrating Virtual and Biochemical Screening for Protein Tyrosine Phosphatase Inhibitor Discovery METHODS 66: 219-228 JAN 2014.
2013
José L Medina-Franco (2013) Advances in Computational Approaches for Drug Discovery Based on Natural Products REVISTA LATINOAMERICANA DE QUÍMICA 41: 2. 95-110.
Clemencia Pinilla, Bruce S Edwards, Jon R Appel, Tina Yates-Gibbins, Marc A Giulianotti, Jose L Medina-Franco, Susan M Young, Radleigh G Santos, Larry A Sklar, Richard A Houghten (2013) Selective Agonists and Antagonists of Formylpeptide Receptors: Duplex Flow Cytometry and Mixture-based Positional Scanning Libraries MOLECULAR PHARMACOLOGY 84: 314-324 SEP 2013.
Jakyung Yoo, Sun Choi, José L Medina-Franco (2013) Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs PLoS ONE 8: 4. e62152.
José L Medina-Franco, Marc A Giulianotti, Gregory S Welmaker, Richard A Houghten (2013) Shifting from the single to the multitarget paradigm in drug discovery DRUG DISCOVERY TODAY 18: 495–501 MAY 2013.
Robert Kraft, Allon Kahn, José L Medina-Franco, Mikayla L Orlowski, Cayla Baynes, Fabian López-Vallejo, Kobus Barnard, Gerald M Maggiora, Linda L Restifo (2013) A cell-based fascin bioassay for multi-purpose compound screening DISEASE MODELS AND MECHANISMS 6: 217-235 JAN 2013.
2012
José L Medina-Franco, Karina Martínez-Mayorga, Terry L Peppard, Alberto Del Rio (2012) Chemoinformatic Analysis of GRAS (Generally Recognized as Safe) Flavor Chemicals and Natural Products PLoS One 7: 11. e50798.
José L Medina-Franco, Jacob Waddell (2012) Towards the Bioassay Activity Landscape Modeling in Compound Databases JOURNAL OF THE MEXICAN CHEMICAL SOCIETY 56: 2. 163-168
Jakyung Yoo, José L Medina-Franco (2012) Computer-guided discovery of epigenetics drugs: molecular modeling and identification of inhibitors of DNMT1 JOURNAL OF CHEMOINFORMATICS 4(Suppl 1): May 2012.
José L Medina-Franco, Austin B Yongye, Jaime Pérez-Villanueva, Richard A Houghten, Karina Martínez-Mayorga (2012) Activity-difference maps and consensus similarity measure characterize structure-activity relationships JOURNAL OF CHEMOINFORMATICS 4(Suppl 1): May 2012.
Fabian López-Vallejo, Jacob Waddell, Austin B Yongye, Richard A Houghten, José L Medina-Franco (2012) A large scale classification of molecular fingerprints for the chemical space representation and SAR analysis JOURNAL OF CHEMOINFORMATICS 4(Suppl 1): P26 May 2012.
2010
Christopher J Armishaw, Narender Singh, Jose L Medina-Franco, Richard J Clark, Krystle C M Scott, Richard A Houghten, Anders A Jensen (2010) A Synthetic Combinatorial Strategy for Developing alpha-Conotoxin Analogs as Potent alpha(7) Nicotinic Acetylcholine Receptor Antagonists JOURNAL OF BIOLOGICAL CHEMISTRY 285: 3. 1809-1821 JAN 15 2010.
Dirk Kuck, Thomas Caulfield, Frank Lyko, Jose L Medina-Franco (2010) Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells MOLECULAR CANCER THERAPEUTICS 9: 11. 3015-3023 NOV 2010.
2009
Narender Singh, Rajarshi Guha, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten, Jose L Medina-Franco (2009) Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository JOURNAL OF CHEMICAL INFORMATION AND MODELING 49: 4. 1010-1024 APR 2009.
Austin B Yongye, Jon R Appel, Marc A Giulianotti, Colette T Dooley, Jose L Medina-Franco, Adel Nefzi, Richard A Houghten, Karina Martinez-Mayorga (2009) Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands BIOORGANIC & MEDICINAL CHEMISTRY 17: 15. 5583-5597 AUG 1 2009.
2008
Karina Martinez-Mayorga, Jose L Medina-Franco, Marc A Giulianotti, Clemencia Pinilla, Colette T Dooley, Jon R Appel, Richard A Houghten (2008) Conformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis BIOORGANIC & MEDICINAL CHEMISTRY 16: 5932-5938 JUN 1 2008.
Alfonso Duenas-Gonzalez, Patricia Garcia-Lopez, Luis Alonso Herrera, Jose Luis Medina-Franco, Aurora Gonzalez-Fierro, Myrna Candelaria (2008) The prince and the pauper. A tale of anticancer targeted agents MOLECULAR CANCER 7: OCT 23 2008.
2007
José L Medina-Franco (2007) Aplicaciones Exitosas del Diseño de Fármacos Utilizando Métodos Computacionales Ciencia 59: 1-8.
Jose L Medina-Franco, Gerald M Maggiora, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten (2007) A similarity-based data-fusion approach to the visual characterization and comparison of compound databases CHEMICAL BIOLOGY & DRUG DESIGN 70: 5. 393-412 NOV 2007.
2006
2005
Olivia Soria-Arteche, Rafael Castillo, Alicia Hernández-Campos, Marcela Hurtado-de la Peña, Gabriel Navarrete-Vázquez, José L Medina-Franco, Kathia Gómez-Flores (2005) Studies on the selective S-oxidation of albendazole, fenbendazole, triclabendazole, and other benzimidazole sulfides JOURNAL OF THE MEXICAN CHEMICAL SOCIETY 49: 4. 353-358.