Welcome to D-Databases!

Here you can find interesting databases that DIFACQUIM has published before, along with a short description and a link to the original reference.

You can use them as an input for D-Tools.

D-DATABASE (D-DB)

D-DB is our latest effort to provide curated high quality data on target annotations of small molecules. For accessing the database click here.

Several public databases that provide either activity information or evidence of direct interaction (e.g., from cocrystalized structures) have been integrated.

D-DB was conceived, designed and developed in collaboration with the research group of Dr. Mónica Campillos from the Helmholtz Zentrum München. We will shortly release more details about the database in a publication.

Other databases

BIOFACQUIM is a free compound database with natural products isolated and characterized in Mexico

Initial version (423 compounds) is accessible here

First update is accessible here

Online access via D-Tools

Epigenomics chemical database

An integrated database of epigenetic inhibitors from various open access databases. Contains data for 54 epigenetic targets along with potency annotations.
Publication (2017): https://doi.org/10.1016/j.drudis.2017.10.006

epidatabase.sdf.zip

Compressed Archive in ZIP Format 3.5 MB

Download

Selected individual targets from the epigenomics chemical database

The zip file contains 5 sdf files each with a chemical library of molecules tested against a particular target, plus DrugBank structures as a reference of a diverse dataset. The selected libraries have varying degrees of diversity. See the publication for further details.

Publication (2017) doi: 10.12688/f1000research.12095.2
DrugBank: https://www.drugbank.ca/

dataset1.zip

Compressed Archive in ZIP Format 1.3 MB

Download

Coming soon ...

Latin American Natural Product Database (LANaPD)

Read commentary in Future Science OA 2020 FSO597

D-InoDB: Towards a Compound Database of Organometallic Drugs for Chemoinformatic Analysis

Presented by: Yazmin Percastre-Cruz el al. at the Third International Conference in Boinformatics, Smulations and Modeling. Talca, Chile. November 5th, 2019.